Check Medication
Interactions Instantly
Enter any two medications to see if they interact — with plain-English explanations and clear recommendations.
Covers prescription drugs, OTC medications, supplements, and common brand names.
Enter Two Medications
Use generic names (e.g. "ibuprofen") or brand names (e.g. "Advil"). Works with supplements too.
Popular medications — click to fill
How the Interaction Checker Works
Simple, fast, and designed to be understood by everyone — not just healthcare professionals.
Enter any two medications
Use generic names, brand names, or common supplements. We recognize hundreds of aliases automatically.
Get instant results
Our database checks for known interactions and returns a clear severity rating — major, moderate, or minor.
Read plain-English guidance
Every result explains what the interaction is, why it matters, and what you should do about it.
Understanding Severity Levels
What each rating means for your safety.
The combination can cause serious harm or be life-threatening. Avoid unless specifically directed by a doctor who is aware of both medications.
The combination may worsen a condition, reduce effectiveness, or increase side effects. Use with caution and inform your doctor or pharmacist.
The interaction is unlikely to cause significant problems for most people, but it's worth being aware of. Monitor for any unusual effects.
Always talk to your pharmacist
This tool covers common interactions but is not exhaustive. Your pharmacist has access to your complete medication history and can provide personalized guidance. Consultations are free and available without an appointment at most pharmacies.